https://www.lymemcw.org/home daily 1.0 2025-01-14 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1542038244877-6ETUJRDCJG5727EZK2NF/CDC+Ixodes+distribution+2018.jpg Home - Overview Learn more about the distribution, transmission, symptoms, and prevention of a variety of tick-borne diseases in the United States. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/65ba95cd-cc2e-4ff1-95b2-4369c76b4507/Bb+persistent+antigen+paper+figure.PNG Home - Research Articles Click on the image to read about our publication outlining the role of peptidoglycan, a major component of the cell wall of Borrelia burgdorferi, as an antigen in Lyme arthritis. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/7eef712b-82c7-4dab-b6e4-712d24b4149a/m_jid_230_suppl_1cover.jpeg Home - Research Articles Click on the button below to read our latest review article on Lyme arthritis. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/76cc7f25-0935-45e9-a59b-7bd29e5ba16f/acr2.v6.10.cover.jpg Home - Research articles Click on the image to read our publication on fibroblasts as inducible antigen-presenting cells: HLA-DR–Expressing Fibroblast-Like Synoviocytes Are Inducible Antigen Presenting Cells That Present Autoantigens in Lyme Arthritis https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/6e5fe78b-3cb1-4e2d-be56-ca983cda6473/Screenshot+2025-01-14+142552.png Home - Research articles Click on the image to read our publication on peptidoglycan and joint inflammation: Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1575407671430-WKLEU1SI776WKFSIAHUZ/Banner+background+Lyme+MCW.jpg Home https://www.lymemcw.org/news-research daily 0.75 2024-12-23 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1610990403368-ZR6EGDPQ8UOXB9MJU4SM/CDC+new+Lyme+diagnosis+estimates+2010-2018+figure.png Published Articles - New CDC Estimates CDC releases new estimate of Lyme disease diagnoses in the U.S. from 2010–2018. Their new value is ~476,000 per year! However, they caution that overdiagnosis can occur and may reach ~19% in low incidence states. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1570635051561-BO4VDAY3YYJATNDB461H/Discovery%2Bof%2Bthe%2BLyme%2BDisease%2BAgent%2Bpaper%2Bscreenshot.jpg Published Articles - Lyme Disease September 2019 article discussing a first-hand account of the discovery of Lyme disease! https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1575400308276-JS77SFROM37PTY7DGAXW/Lyme+springtime+vaccine+article+screenshot.png Published Articles - Lyme Disease Springtime “vaccine” for Lyme disease will begin testing on human subjects. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546272005016-5ZMZDNC6BYQTM0PUL9AV/Powassan+tick+saliva+paper+screenshot.png Published Articles - Powassan Virus 2015 study showing that tick saliva enhances disease transmission when low doses of Powassan virus are present in mice https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546458652503-UKKW2IOFIHY5G4HTJG5H/Lyme+genetically+modified+mice+article+screenshot.png Published Articles - Playing God? 2016 NPR article discussing the use of genetically engineered Lyme-resistant mice as a way to control Lyme disease https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546274355782-Z2G9237F2E79MNCIIZW7/Lone+star+ticks+red+meat+allergy+news+screenshot.png Published Articles - Lone Star Ticks 2018 NPR article showing red meat allergies can be caused by the bite of a lone star tick https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1571257102015-4EJF1BVFWU8E2FASX7WW/Babesiosis+and+lyme+coinfection+paper+screenshot.png Published Articles - Co-infection September 2019 review article highlighting key facts of Lyme disease/babesiosis co-infections. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/a8b8897b-bd37-4c8e-97e3-6c5a10ddc40e/Screenshot+2024-09-30+125459.png Published Articles - Lyme Disease 2024 paper describing the role of fibroblasts as antigen presenting cells in Lyme Arthritis. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550166910804-EPEJM4C4SC1O6WPPSB06/Lyme+Wars+article+screenshot.png Published Articles - The Lyme Wars Informative article published in the New Yorker in 2013 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550774707501-UXXLY5YTGP0LYB3PW2XW/Lyme+autoantigen+paper+screenshot.png Published Articles - Lyme Disease 2018 paper highlighting the discovery of a new autoantigen for persistent Lyme disease symptoms https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1562607074893-RUI0NLWWMUYZ96HCJ7NN/Lyme%2Bvaccine%2Barticle%2Bscreenshot.jpg Published Articles - Lyme Disease 2019 article explaining the controversy surrounding the Lyme disease vaccine https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/a8b9f5b0-4862-444f-8196-9162c0a0ba43/Screenshot+2024-09-30+134034.png Published Articles - Lyme Disease 2024 paper discussing MHC-II epitopes presented during infection with Borellia burgdorferi https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1562011520664-VHQIZAI9ISIOWS5OIE6Z/Multiplex+serology+paper+screenshot.png Published Articles - Tick-borne Diseases 2018 paper discussing the development of the first multiplex serodiagnostic assay for the detection of 8 major tick-borne diseases. The assay can detect concurrent infections, as well as asymptomatic or past infections! https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/423847bb-7079-42bc-b01d-f3810f07b3b6/Bb+phospholipid+paper+screenshot.PNG Published Articles - Lyme disease 2022 paper discussing B. burgdorferi phospholipid autoantibodies in Lyme disease and potential use in diagnostics. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/cbd49f6c-520b-4422-b822-9d243e7e162c/Screenshot+2024-09-30+133304.png Published Articles - joint inflammation 2024 paper describing the association of peptidoglycan with joint inflammation in osteoarthritis https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546550542223-Q8DX4LXRZ4611FIH0400/Lyme+disease+IgM+antibody+paper+screenshot.png Published Articles - Lyme Disease 2018 paper demonstrating increased sensitivity and specificity in serological diagnosis for Lyme disease https://www.lymemcw.org/anaplasmosis daily 0.75 2019-07-02 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550241796407-YOCRPHNR7KD20GA9P14M/Anaplasmosis+reported+cases.png Anaplasmosis Number of U.S. anaplasmosis cases reported to CDC, 2000–2016 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550241852739-VZDLWEDLM03NE8SAIOPA/Anaplasmosis+month+of+onset.png Anaplasmosis Number of reported anaplasmosis cases by month of onset, 2000–2016 (Source: CDC) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550241898748-GJGVP7I0AP88GC9HAE4X/Anaplasmosis+US+map.png Anaplasmosis Annual reported incidence (per million population) for anaplasmosis – United States, 2016. (NN= Not notifiable) (Source: CDC) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550242224731-PDPWD90ETRSL2JCZ6OR2/Anaplasma+phagocytophilum+staining.jpg Anaplasmosis Wright-Giemsa-stained peripheral blood smear of Anaplasma phagocytophilum https://www.lymemcw.org/powassan-virus daily 0.75 2019-07-02 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550255538444-LPQDEN0SHGKLBCDDVUG7/Powassan+virus.jpg Powassan Virus Computer illustration of Powassan virus particles. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550255789948-9N0AYXGJ8OH7683AWHZP/Powassan+virus+reported+cases+graph.jpg Powassan Virus Powassan virus cases reported by year, 2008–2017 (Source: CDC) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550255846238-SCFY18657PKLQL7D8S6V/Powassan+virus+US+map.jpg Powassan Virus Powassan virus cases reported by state of residence, 2008–2017 (Source: CDC) https://www.lymemcw.org/lyme-disease-1 daily 0.75 2022-03-15 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1541294498309-WHD1ODIT6IEFT7PWG76R/Borrelia+phase+contrast.png Lyme Disease Phase contrast image of Borrelia burgdorferi (Image credit: Brandon Jutras, Yale) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1541295270488-TQYUT9NGRR2P9QE0Q6XV/LD+symptoms.png Lyme Disease Source: CDC (click to enlarge) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1541294992690-X82QBISWUVMSJLYMVMA2/LD+reported+cases+2001.png Lyme Disease https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1647355266691-C4LSRQHMPZLJYHE1SCV2/Lyme+disease+map+cases+2019.jpg Lyme Disease https://www.lymemcw.org/babesiosis daily 0.75 2019-02-15 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550242661336-3KWOCJDCOJN2GYKNBN79/Babesia+staining.gif Babesiosis Morphology of Babesia in an erythrocyte, as seen in Geimsa staining of a thin blood smear. (Source: Stanford) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550243159620-FTO1ALFJUJ1EYKC59TTU/Babesiosis+reported+cases+map.jpg Babesiosis Number of reported cases of babesiosis, by county of residence — 31 states, 2014. Cases are mapped to the patients’ county of residence, which was not necessarily where they became infected. Babesiosis was not a reportable disease in the gray states, and health departments in those states did not notify CDC of cases. (Source: CDC). Click to enlarge. https://www.lymemcw.org/tick-ecology daily 0.75 2019-07-02 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546444006996-YZ4HQRVJPM65BIRMUHPA/Tick+prevention+in+yard.jpg Tick Ecology Source: CDC (click to enlarge) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546443617627-ZPEX6U54GATC8JX4KK6U/Tick+prevention+on+people.jpg Tick Ecology Source: CDC https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546443705466-ZZJP8DX5UC9DFPNMW8ZA/Tick+prevention+on+pets.jpg Tick Ecology Source: CDC https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1541440304985-MQ9MG6JRFGNA1PZKW66I/Ixodes+scapularis+life+cycle.png Tick Ecology Source: CDC https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546443010106-AL0I0ATNN2GAVOP2SW7Y/American+dog+tick+distribution.jpg Tick Ecology American dog tick distribution (CDC). https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1542663465025-5XWLYRLUD200Z3BU13UP/Ixodes+distribution+2018.jpg Tick Ecology Ixodes scapularis estimated and established distribution, 2018. Estimated distribution of the blacklegged tick (Ixodes scapularis) is shown in yellow. Counties where established populations have been documented are shown in red. Counties classified as “established” are those where six or more I. scapularis of a single life stage or more than one life stage of the tick were collected in the county within a 12-month period (CDC). https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1542663270037-NK89W9HRNJKCXDX0T9DX/Tick+sizes.jpg Tick Ecology Relative sizes of ticks at different life stages (CDC). https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546443191030-D75J1GPDMKVA2TMS8FAS/Brown+dog+tick+distribution.jpg Tick Ecology Brown dog tick distribution (CDC). https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1546440170173-LAE9GNU33G1RESI5SOLS/Lone+star+tick+distribution.jpg Tick Ecology Lone star tick distribution (CDC). https://www.lymemcw.org/resources daily 0.75 2018-12-10 https://www.lymemcw.org/ehrlichiosis daily 0.75 2019-02-15 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550254601436-LQWIN7K09H965SN68ZTK/Ehrlichiosis+reported+cases.png Ehrlichiosis Number of U.S. ehrlichiosis cases caused by Ehrlichia chaffeensis and reported to CDC, 2000–2017 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550254654215-V4QPTUVNW7UZPHPLDE1I/Ehrlichiosis+month+of+onset.png Ehrlichiosis Number of reported ehrlichiosis cases caused by Ehrlichia chaffeensis by month of onset, 2000–2017 (Source: CDC) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550254713881-TU4KV4IX2RS8BPN1SIZG/Ehrlichiosis+US+map.png Ehrlichiosis Annual reported incidence (per million population) for E. chaffeensis in the United States for 2017. (NN= Not notifiable) (Source: CDC) https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1550243784005-D115K5SO05XHR2WLMV1X/Ehrlichia+staining.png Ehrlichiosis Wright stain of peripheral blood smear showing Ehrlichia chaffeensis https://www.lymemcw.org/powassan-virus-1 daily 0.75 2019-01-29 https://www.lymemcw.org/for-educators daily 0.75 2019-07-10 https://www.lymemcw.org/babesiosis-1 daily 0.75 2019-02-14 https://www.lymemcw.org/ehrlichiosis-1 daily 0.75 2019-02-25 https://www.lymemcw.org/lyme-disease-2 daily 0.75 2021-03-31 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/1543269262624-YG7ICK18EY42OS0QVPE2/Serodiagnostic+tests+lyme+disease+table.png Lyme Disease Evolution of serodiagnostic testing for Lyme disease in the U.S. (Branda et al. 2017) Click to enlarge. https://www.lymemcw.org/anaplasmosis-1 daily 0.75 2019-01-03 https://www.lymemcw.org/lochhead-scientific daily 0.75 2025-02-04 https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/60a69c17-cac8-4e79-a8cd-69689c26e53e/Screenshot+2025-02-04+110016.png Lochhead Scientific - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5bc639dce5f7d10651a03836/94434a98-3ca4-47ef-ae6d-a9640aa58e47/Screenshot+2025-01-28+111336.png Lochhead Scientific - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.lymemcw.org/partners-bedford daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390409437321-Q9EZYDA52XWMFWJIQRU6/logo-2.jpg Partners https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390409437266-8DADKO4VSI8O9JEYQ58I/logo-4.jpg Partners https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390409437284-U9500QOC95REDBT90G9L/logo-1.jpg Partners https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390409437242-8SZY5F04GD012C425QZ6/logo-3.jpg Partners https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390505394162-W51WFS0M8F9TXWY7LPDY/chambers-10.jpg Partners https://www.lymemcw.org/home-alt-bedford daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390500612440-PGQSIY8KL9F7T5VIXQLO/chambers-2.jpg Home Alt A better world Starts with a choice Contact Us https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390500503574-5BAPXZO9U06UV61P49UO/chambers1.jpg Home Alt Sustainability Starts with you Join Us https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390500933384-LII4SRIPHFYOUFX0UCXC/chambers-4.jpg Home Alt A better world Starts with a choice Join Us https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390504287124-HQ8GNX1JCE22V047MSQ9/chambers-8.jpg Home Alt Preserve Nature Join Us https://www.lymemcw.org/projects-bedford daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390513827835-7X0ZFXSD0X2H8JVTM0G7/tumblr_mqvsd7ij1c1rkz363o1_1280.jpg Projects https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390513704892-X6RLQ8I6CZ7RH14SLT95/tumblr_mjco89cUVY1rkz363o1_1280.jpg Projects https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390513762052-20QA8XOF4PAJV9MQ8VIT/tumblr_mlsetsKySj1rkz363o4_1280.jpg Projects https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390597386640-3KVLE657DTIG7GJ4AQE2/tumblr_mjdttrQLOJ1rkz363o7_1280.jpg Projects